The loss of tone on face and body is due to multiple endogenous and exogenous factors. Over time, fibroblasts slow down their activity resulting in a decreasing in the production of collagen and elastin. Not only the number, but also the size of structural proteins decrease. In this way a real thinning of the dermis is obtained which has as a direct consequence a structural failure.
Derma-Firming® cocktail is a powerful mix based on highly concentrated active ingredients: DMAE firming fluid, Organic silicon, Rejuline complex ™, Hyaluronic Acid High molecular weight, Hyaluronic Acid Low molecular weight, Hydroxyproline, Proline, Lysine, Glycine, Acetyl Cysteine.
1% organic silicon: acts in tissues as a catalyst against various reactions. Promotes the synthesis of collagen and elastin, improving the connective structures. It is a structural component of the connective tissue that forms part of the most important macro-molecules such as elastin and collagen. At the tissue level it induces the control and proliferation of fibroblasts, favoring the regeneration of elastic fibers and collagen and preventing their premature degradation.
DMAE firming fluid 7%: this is a neuromodulator and protects the bonds between collagen and elastin. It is mainly used to produce a tensor effect thanks to receptor communication with keratinocytes, fibroblasts, myofibroblasts and endothelial cells that respond to acetylcholine; it also acts as a collagen stimulator, derived from a receptor response of fibroblasts. Thus there is a progressive cytoplasmic concentration of myofilaments. Repairs the collagen and elastin fibers and, at different levels, allows to obtain: increase in tension in non-muscle cells of the dermis, increase in cohesion and displacement of keratinocytes, increase in hydration and elasticity of the stratum corneum, increase in the supply of nutrients and defense mechanisms. It also acts as an antioxidant and repairs collagen and elastin fibers from damage caused by free radicals;
Rejuline Complex ™: This special patented peptide complex allows to bio-stimulate cell regeneration through the improvement of anabolic mechanisms, strengthens the elasticity and tone of the tissues (by inducing the synthesis of new collagen, elastin, fibronectin and laminin). Increases the expression level of extracellular matrix proteins such as elastin, collagen, fibronectin and laminin and the production of procollagen already after 7 days;
Hyaluronic Acid with high and low molecular weight allows to ensure the maximum percentage of water necessary to “restart” all metabolic processes as well as significantly reduce the excessive trans epidermal evaporation of water while maintaining elastic and toned tissues;
essential amino acids (Hydroxyproline, Proline, Lysine, Glycine, Acetylcysteine) to provide the necessary nourishment.
Facial Skin lifting treatment with biomimetic peptides Argireline 5% and Leuphasyl 5% Derma-Lifting®
Argireline 5% and Leuphasyl 5% are a combined chain of 11 amino acids and are the main substances known for their relaxing effects on the skin. With the continuous alternation of contraction and relaxation of the mimic muscles, the daily passing of time and the progressive weakening of the dermal matrix, there is the appearance of signs of a dynamic type called expression lines. The Derma-Lifting® cocktail skin lifting treatment aims to counteract this type of imperfection by acting like a botox and significantly reducing the contraction of the mimic muscles responsible. The combination of active ingredients such as peptides like Argireline and Leuphasyl are essential to give a lifting and firming effect. Derma Lifting facial lifting treatment with biomimetic peptides is an effective alternative to the best known lifting anti-wrinkle techniques. It is perfect for clients who want the lifting effects of Botox without any loss of facial expression.
Argireline (acetyl hexapeptide-8) is a chain of 6 amino acids, responsible for the soothing of the skin. The non-entry of leuphasyl into the muscle and the modulation by argirelin in the formation of the SNARE complex (set of integral membrane proteins), attenuate muscle contraction. Leuphasyl (pentapeptide-18) interacts with the receptors for the enkephalins and closes the calcium channels by inhibiting the release of acetylcholine in the synapses. They are known for their ability to reduce expression lines and prevent new ones.This latest generation of peptides lifting treatment product reduces and prevents expression lines by inhibiting muscle contraction and is ideal for those faces with many expression lines.
Improved tone, a more radiant and relaxed appearance, greater elasticity and compactness are just some of the benefits thanks to Derma-Bio biorevitalisation cocktail. Thanks to the innovative complex of 3 different molecular weights of hyaluronic acid (Low, medium and high), vitamin A, vitamin B, vitamin C and E, as well as amino acids, DMAE, peptides, sodium DNA and antioxidants acting in synergy to give more hydration, homogeneity of texture, elasticity and tone. After just 4 weeks, there is a considerable improvement in general state of the skin and a brighter, relaxed and visibly more uniform appearance.
SODIUM HYALURONATE (hyaluronic acid) at 3 different molecular weights
It is the sodium salt of hyaluronic acid (hyaluronic acid + sodium hydroxide) used for its greater ability to be absorbed in the skin. In Derma-Bio biorevitalising treatment (biorevitalisation cocktail) is present in three molecular weights:
High molecular weight: given its viscosity (it is not absorbed) it carries out its action at the epidermal level where it acts as a humectant given the remarkable hydration capacity (greater turgor); it is a film-forming compound that prevents the transdermal dispersion of water.
Low molecular weight: acts and penetrates up to the dermis where it acts as a filler and stimulates the synthesis of collagen fibers;
Medium molecular weight: it has intermediate characteristics between the two previous ones;
BIOREVITALISING FACE MULTIVITAMIN COMPLEX
VITAMIN A PALMITATE (RETINOL) Esterified form (with palmitic acid) of retinol, more easily absorbed (it is converted first into retinol and then into retinoic acid). At epidermal level, it stimulates cell turnover giving a smoother appearance to the skin; contributes to the proliferation of keratinocytes. At dermal level, it stimulates the production of collagen and elastin (in synergy with vitamin E);
VITAMIN E ACETATE or alpha tocopherol acetate is commonly used as a natural preservative. At dermo-epidermal level (in synergy with vitamin A) it has functions: antioxidant and elasticizing, nourishing, anti-inflammatory and pro-reparative, sebum-regulating;
VITAMIN B1 (thiamine) necessary for the metabolism of carbohydrates (provides energy to the cells). Useful for cell growth when it acts in synergy with vitamin B6;
VITAMIN B3 (niacinamide) acts as an antioxidant, sebum regulator, cofactor in the synthesis of keratin and ceramides, moisturizer, keratinolytic differentiation factor;
VITAMIN B6 (pyridoxine) necessary for the metabolism of proteins, carbohydrates and fatty acids. A deficiency causes peeling and overproduction of the skin. It intervenes as a cofactor in the synthesis of collagen and cysteine, an amino acid useful for the well-being of nails and hair as well as for the synthesis of glutathione;
VITAMIN B8 (biotin) is involved in the synthesis of fatty acids and in the metabolism of proteins and carbohydrates. On the skin, it has a sebum-regulating action and contributes to the synthesis of keratin for maintaining the well-being of the tissues.
VITAMIN C (ascorbic acid) with antioxidant and intrinsic and extrinsic anti-aging (photo-protection) action. At dermal level it helps to maintain the adequate density of collagen by regulating the enzymatic synthesis activity.
AMINO ACID COMPLEX FOR FACE BIOREVITALISATION
GLYCINE The simplest of the amino acids and the main constituent of NMF and collagen. It is used on dry and inelastic skin as it has a moisturizing, repairing and antioxidant action.
L-PROLINE Together with glycine, this amino acid is the main constituent of collagen (niacin and vitamin C are used as synthesis cofactors).
L-HYDROXYPROLINE It is the proline which undergoes a post synthesis modification (hydroxylation); contributes to the production of collagen.
L-ARGININE Alkaline amino acid, present in NMF with moisturising, anti-aging, vasodilatory properties (hair well-being);
ANTIOXIDANTS, BIOMIMETIC PEPTIDES AND STIMULANTS FOR BIOREVITALIZATION
DMAE Analog of choline (precursor of acetylcholine) with anti-aging, antioxidant and moisturising, vasoprotective functions;
ARGIRELINE (acetyl hexapeptide 8) Biomimetic peptide that mimics the effect of botulinum neurotoxin (competition on SNARE complex), causing distension and relaxation on the skin.
SODIUM DNA Sodium salt of deoxyribonucleic acid, used in immune cosmetics for its pro-regenerating properties, stimulating cell proliferation, pro-reparative, stimulating the synthesis of collagen and elastin;
GLUTATHIONE Tripeptide (glycine + glutamate + cysteine) which acts as a powerful antioxidant in particular when it works in synergy with selenium, B3, B6 and E. It gives brightness, tone and elasticity.
Complete stretch mark and scar treatment cocktail, 5x5ml sterile vials. Powerful mix of active substances with a cutting-edge formulation able to correct scars (especially as a treatment for acne scars), and revascularize stretch marks, even white ones thanks to an innovative active ingredient (PSEUDOALTEROMONAS extract) and to the synergy of a patented peptide complex (in particular Acetyl Tripeptide-30, Pentapeptide-18), amino acids (L-Arginine, L-Proline, Glycine, Citrulline) wisely combined with a high concentration of D-Panthenol and Centella asiatica extract.
Continuous elastic stresses of the tissue (as a result of weight loss/gain, lifestyle, age and trauma) are co-factors of the degradation of the dermal matrix, at the basis of problems such as stretch marks and scars.
Ingredients of Derma-Repair cocktail: Pseudoalteromonas extract, D-Panthenol, Centella asiatica extract, L-Arginine, L-Proline, Glycine, Citrulline, Acetyl Tripeptide-30, Pentapeptide-18, Sodium hyaluronate.
Pseudoalteromonas extract: a discovery in the aesthetic and medical fields; this exopolysaccharide exerts a very powerful restructuring action used above all as a stretch mark treatment and scar treatment;
D-Panthenol which acts as an activator of the proliferation of fibroblasts;
Centella asiatica extract, a powerful healing agent that increases the fibrillar content of the connective tissue;
Amino acid complex: L-Arginine, L-Proline, Glycine, Citrulline;
Biomimetic peptides, Acetyl Tripeptide-30, Pentapeptide-18
Sodium hyaluronate plays an important restructuring role on scars and stretch marks, giving uniformity of texture.